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compound 11b  (ATCC)
99
ATCC compound 11b
Compound 11b, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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crystal structure of compound 11b  (Cambridge Crystallographic)
90
Cambridge Crystallographic crystal structure of compound 11b
Crystal Structure Of Compound 11b, supplied by Cambridge Crystallographic, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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crystal structure of compound 11b - by Bioz Stars, 2026-03
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compounds 11a , 11b , 11d , 11e , and 11f  (Muegge GmbH)
90
Muegge GmbH compounds 11a , 11b , 11d , 11e , and 11f
Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / <t>11f</t> : R 1 = C 5 H 11 , R 2 = H).
Compounds 11a , 11b , 11d , 11e , And 11f, supplied by Muegge GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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compounds 11a , 11b , 11d , 11e , and 11f - by Bioz Stars, 2026-03
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compound 11b  (Selleck Chemicals)
96
Selleck Chemicals compound 11b
Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / <t>11f</t> : R 1 = C 5 H 11 , R 2 = H).
Compound 11b, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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compound 11b - by Bioz Stars, 2026-03
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compound 11b treatment  (Selleck Chemicals)
96
Selleck Chemicals compound 11b treatment
Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / <t>11f</t> : R 1 = C 5 H 11 , R 2 = H).
Compound 11b Treatment, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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compound 11b  (DiscoverX corporation)
90
DiscoverX corporation compound 11b
Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / <t>11f</t> : R 1 = C 5 H 11 , R 2 = H).
Compound 11b, supplied by DiscoverX corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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j compounds asoprisnil [benzaldehyde4- [(11b,17b)-17-methoxy-17-(methoxymethyl)-3oxoestra-4,9-dien-11-yl]-1-oxime  (Jenapharm GmbH Co KG)
90
Jenapharm GmbH Co KG j compounds asoprisnil [benzaldehyde4- [(11b,17b)-17-methoxy-17-(methoxymethyl)-3oxoestra-4,9-dien-11-yl]-1-oxime
Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / <t>11f</t> : R 1 = C 5 H 11 , R 2 = H).
J Compounds Asoprisnil [Benzaldehyde4 [(11b,17b) 17 Methoxy 17 (Methoxymethyl) 3oxoestra 4,9 Dien 11 Yl] 1 Oxime, supplied by Jenapharm GmbH Co KG, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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j compounds asoprisnil [benzaldehyde4- [(11b,17b)-17-methoxy-17-(methoxymethyl)-3oxoestra-4,9-dien-11-yl]-1-oxime - by Bioz Stars, 2026-03
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compounds r mrsa atcc 43300 s aureus atcc 29213 hn15 sa1 e coli atcc 25922 11b o  (ATCC)
99
ATCC compounds r mrsa atcc 43300 s aureus atcc 29213 hn15 sa1 e coli atcc 25922 11b o
Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / <t>11f</t> : R 1 = C 5 H 11 , R 2 = H).
Compounds R Mrsa Atcc 43300 S Aureus Atcc 29213 Hn15 Sa1 E Coli Atcc 25922 11b O, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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compounds r mrsa atcc 43300 s aureus atcc 29213 hn15 sa1 e coli atcc 25922 11b o - by Bioz Stars, 2026-03
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Image Search Results


Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / 11f : R 1 = C 5 H 11 , R 2 = H).

Journal: International Journal of Molecular Sciences

Article Title: Naphthoquinone-Quinolone Hybrids with Antitumor Effects on Breast Cancer Cell Lines—From the Synthesis to 3D-Cell Culture Effects

doi: 10.3390/ijms25126490

Figure Lengend Snippet: Synthetic route towards 1,4-naphthoquinone/4-quinolone conjugates. a: (1) EMME, EtOH; (2) Diphenylether, 250 °C; b: (1) K 2 CO 3 , DMF, r. t., 15 min. (2) R1-X, DMF, 80 °C, 24 h.; c: H 2 (20 bar), Pd/C (10%), EtOH, 50 °C, 3 h. (for R1 = ethyl and pentyl); d: NH 4 Cl 0,05 M, Fe, reflux (for R1 = benzyl); e: (1) NaOH, EtOH, r. t. (2) H 2 O, HCl; f: t-butyl nitrite, DMSO, H 2 O, 1,4-naphthoquinone, ultrasound, 25 °C. ( 15a/11a : R 1 = Et, R 2 = Et; 15b/11b : R 1 = Bn, R 2 = Et; 15c / 11c : R 1 = Pentyl, R 2 = Et; 16a / 11d : R 1 = Et, R 2 = H; 16b / 11e : R 1 = CH 2 C 6 H 5 , R 2 = H; 16c / 11f : R 1 = C 5 H 11 , R 2 = H).

Article Snippet: Additionally, compounds 11a , 11b , 11d , 11e , and 11f exhibited zero violations of the drug-likeness rules of Lipinski, Ghose, Veber, Egan, and Muegge.

Techniques: Reflux

IC 50 values and selectivity indices (SI) of 1,4-naphthoquinone, compounds 11a–f , and doxorubicin.

Journal: International Journal of Molecular Sciences

Article Title: Naphthoquinone-Quinolone Hybrids with Antitumor Effects on Breast Cancer Cell Lines—From the Synthesis to 3D-Cell Culture Effects

doi: 10.3390/ijms25126490

Figure Lengend Snippet: IC 50 values and selectivity indices (SI) of 1,4-naphthoquinone, compounds 11a–f , and doxorubicin.

Article Snippet: Additionally, compounds 11a , 11b , 11d , 11e , and 11f exhibited zero violations of the drug-likeness rules of Lipinski, Ghose, Veber, Egan, and Muegge.

Techniques:

Physicochemical parameter values for compounds 11a–f using Swiss ADME server.

Journal: International Journal of Molecular Sciences

Article Title: Naphthoquinone-Quinolone Hybrids with Antitumor Effects on Breast Cancer Cell Lines—From the Synthesis to 3D-Cell Culture Effects

doi: 10.3390/ijms25126490

Figure Lengend Snippet: Physicochemical parameter values for compounds 11a–f using Swiss ADME server.

Article Snippet: Additionally, compounds 11a , 11b , 11d , 11e , and 11f exhibited zero violations of the drug-likeness rules of Lipinski, Ghose, Veber, Egan, and Muegge.

Techniques: